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Type 2 Diabetes With Obesity# Recommendation : CagriSema Reason : REDEFINE 2 showed 13.7% weight loss with 73.5% of T2D patients achieving HbA1c of 6.5% or less, exceeding semaglutide's glycemic and weight results in T2D trials
Generally, GLP-1 induced nausea will ease after a few weeks of taking the medication
Furthermore, GLP-1 RAs exhibit anti-inflammatory effects, lowering circulating levels of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interleukin-1 beta (IL-1), and IL-6, while promoting anti-inflammatory mediator production [26]
Dosing Research protocols vary depending on application: Topical: creams or serums for skin and hair
glutathione for overall neuroprotection